Senior Research Scientist
hace 4 semanas
Dewpoint Therapeutics is a pioneering company that's harnessing the power of biomolecular condensates to revolutionize drug discovery. We're seeking an experienced and driven Scientist/Sr. Scientist to join our team and contribute to the development of breakthrough therapeutics for metabolic diseases.
About the RoleWe're looking for a highly skilled professional with a deep understanding of metabolic diseases and a proven track record in setting up and conducting functional assays in human cellular disease models. As a key member of our team, you'll be responsible for developing and optimizing functional assays to support the hit-to-lead optimization process for small molecule candidates targeting metabolic diseases.
Key Responsibilities- Develop and optimize functional assays to evaluate the efficacy of potential therapeutic compounds
- Conduct functional assays in human skeletal muscle, human adipocyte, and primary human hepatocyte models
- Establish and maintain scalable assays that can be run at a high cadence for effective hit triaging
- Collaborate with cross-functional teams to align assay development with project goals
- Lead the progression of compounds through the screening decision tree
- Ph.D. or equivalent in metabolic diseases or a related field
- At least 5 years of experience in metabolic disease research
- Extensive experience in developing and conducting functional assays
- Proven experience with human iPSC culture and differentiation
- Deep biological understanding of metabolic disease pathways
Dewpoint Therapeutics is a leader in the field of biomolecular condensates and is committed to cultivating an inclusive international community that welcomes and empowers everyone. We're an equal opportunity employer and welcome applications from diverse candidates.
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