Technical Lead MES

We are seeking an experienced Technical Lead MES to join a global digital manufacturing transformation program. The Technical Lead will provide end-to-end technical leadership for Manufacturing Execution System (MES) implementations based on the PAS-X platform. This role will ensure technical consistency, implementation quality, system integration, and alignment with enterprise and manufacturing standards. The ideal candidate will have strong hands-on experience with MES/MOM, PAS-X, OT/IT integration, and manufacturing environments, along with the ability to collaborate effectively with technical and business stakeholders across multiple sites.

Key Responsibilities
• Lead technical and architectural decisions related to the MES/PAS-X implementation program.
• Ensure alignment between global core models and local site implementations while minimizing unnecessary customizations.
• Define and govern configuration, integration, and development standards.
• Coordinate technical activities with vendors, system integrators, automation providers, and infrastructure teams.
• Support Program Managers and Deployment Leads on technical and solution-related matters.
• Oversee MES configuration activities, including workflows, forms, MBRs, gMBRs, and ESP.
• Manage and support integrations with enterprise and shop-floor systems, including ERP, SCADA, LIMS, and Historian.
• Ensure proper implementation of OT/IT interfaces and integration patterns.
• Support master data management and alignment processes.
• Validate technical solutions against functional and technical requirements.
• Lead technical activities related to System Integration Testing (SIT), User Acceptance Testing (UAT), defect management, and go-live.
• Support validation and qualification activities in regulated environments.
• Oversee deployment, go-live, and technical stabilization activities.
• Troubleshoot and resolve complex technical issues throughout project execution.
• Develop and maintain technical documentation and implementation guidelines.
• Facilitate knowledge transfer to local teams and support organizations.
• Promote solution standardization, scalability, and reusability across manufacturing sites.
• Support continuous improvement initiatives within the MES program. Required Qualifications
• 6–8 years of proven experience implementing MES/MOM solutions in industrial manufacturing environments.
• Hands-on experience with the PAS-X platform, including MES/MOM solutions and OT/IT integrations.
• Strong knowledge of:
• Enterprise and OT application architectures
• MES configuration, implementation, and deployment
• System integration and interface design
• Manufacturing processes
• Master Data Management
• OT/IT integration
• Experience working on multi-site deployment programs.
• Strong knowledge of the ISA-95 standard.
• Experience with SIT, UAT, defect management, and go-live activities.
• Ability to work effectively with technical and business stakeholders, including IT, OT, Manufacturing, and Quality teams.
• Native or near-native Spanish proficiency.
• Professional working proficiency in English. Preferred Qualifications
• Experience in regulated industries, particularly Pharmaceuticals or Life Sciences.
• Knowledge of validation methodologies and compliance frameworks such as:
• GAMP 5
• Computer System Validation (CSV)
• Experience designing scalable architectures.
• Experience supporting cross-site standardization initiatives.
• Familiarity with global MES deployment programs and template-based rollouts. Key Competencies
• Technical Leadership
• Problem Solving
• Stakeholder Management
• Cross-Functional Collaboration
• Communication Skills
• Analytical Thinking
• Decision Making
• Technical Troubleshooting
• Continuous Improvement Mindset