Postdoctoral Research Scientist

hace 2 semanas


Puerto Diablo Barrio, Puerto Rico Jobleads-Us A tiempo completo

Employer Description Massachusetts General Hospital

The Tearney Lab is an 80+ person multidisciplinary lab led by Guillermo (Gary) Tearney, MD, PhD. The goal of the Tearney Lab is to see every cell in the human body so that disease can be detected at its earliest stages when it can be cured.

The lab has pioneered multiple optical coherence tomography (OCT) devices that enable 3D imaging at the microscopic scale in living human patients. These technologies include multimodality OCT where OCT is combined with spectroscopy, fluorescence, and other optical techniques, ultrahigh-resolution OCT (μOCT) where the resolution is sufficiently detailed to visualize individual cells, and functional OCT that measures the function and metabolism of cells in living systems.

To enable this broad translational research, the Tearney Lab is outfitted with:

Robust engineering, quality, and clinical regulatory teams, state-of-the-art optical laboratories, two class 10,000 clean rooms, and multiple rapid prototyping facilities. The lab also has a nanoscribe optical printing machine and a machine learning core.

The role will involve developing novel fiber optic probes, illumination, and detection systems with suitable sensitivities for biological imaging. It will also involve developing novel optical devices based on optical modalities such as spectrally encoded confocal microscopy, multi-photon microscopy, and photoacoustics.

Additionally, the role will involve developing novel OCT-based devices for in-vivo imaging, including high-resolution micro-OCT, dynamic OCT, fluorescence OCT, white light OCT, diffuse reflectance OCT, and OCT combined with ultrasound. The successful candidate will also be responsible for implementing technologies in one or more of the following organ systems: heart, lungs, brain, ears, and the gastrointestinal tract.

The role will also involve guiding research questions, designing studies, and monitoring the execution of those studies. The candidate will guide and oversee engineers and technicians on the research aspects of their projects, ensuring they are being done to a scientifically valid and publishable standard.

The candidate will also be responsible for holding regular technical meetings, setting the agenda, and outlining a sequence of work for technicians and engineers to follow. They will also be responsible for publishing in world-leading high-impact journals and delivering milestones on time.

This appointment will be made at the rank of postdoctoral fellow or instructor at Harvard Medical School, commensurate with the applicant's experience. MGH's role as a leading teaching affiliate of Harvard Medical School and close ties to Harvard University and MIT provide an outstanding environment for developing and translating new OCT technologies with applications in basic and clinical research.

Job Requirements A PhD (or equivalent) in Biomedical Engineering, Electrical Engineering, Physics, or a related field is required. Required Skills Demonstrated excellence in one of the various forms of optical coherence tomography, confocal microscopy, or other in vivo microscopy techniques is required. Expertise in one or more of the following areas is desired: optical imaging systems, optical design, circuit design, optical system fabrication, fiber optic systems and components, broadband light source development, spectroscopy, image processing, programming, and clinical studies with novel devices.

A strong grounding in fundamental optics theory, including fiber optic light guides, is also required. A strong understanding of tissue optical properties is desired. Desired Skills Experience in modeling of light/tissue interactions, a background in fiber probe design, and a strong computational background are also desired. An organized and creative problem-solver is essential for this role.

Contact Information Interested candidates are encouraged to send a CV accompanied by a cover letter describing any previous research training, specific areas of interest, and contact information for three letters of reference. Address correspondence to Dr. Gary Tearney, noting the position being applied for in the subject line, and send by email to the provided address.

MGH is an equal opportunity employer.

Key Responsibilities

  1. Develop novel fiber optic probes, illumination, and detection systems with suitable sensitivities for biological imaging.
  2. Develop novel optical devices based on optical modalities such as spectrally encoded confocal microscopy, multi-photon microscopy, and photoacoustics.
  3. Develop novel OCT-based devices for in-vivo imaging, including high-resolution micro-OCT, dynamic OCT, fluorescence OCT, white light OCT, diffuse reflectance OCT, and OCT combined with ultrasound.
  4. Implement technologies in one or more of the following organ systems: heart, lungs, brain, ears, and the gastrointestinal tract.
  5. Guide research questions, design studies, and monitor the execution of those studies.
  6. Guide and oversee engineers and technicians on the research aspects of your projects and ensure they are being done to a scientifically valid and publishable standard.
  7. Publish in world-leading high-impact journals.
  8. Deliver milestones on time.


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